Which medication is commonly used to manage nausea during pregnancy?

The choice that indicates "All of the above" is correct because all listed medications—ondansetron, promethazine, and metoclopramide—are indeed used to manage nausea during pregnancy.

Ondansetron is a serotonin 5-HT3 receptor antagonist commonly prescribed to alleviate nausea and vomiting, especially severe cases like hyperemesis gravidarum. It is often favored due to its effectiveness and a relatively low side effect profile when used during pregnancy.

Promethazine is an antihistamine that also has antiemetic properties. It is frequently utilized to treat various types of nausea and can be especially useful for motion sickness and nausea related to anesthesia.

Metoclopramide is a prokinetic agent that increases gastrointestinal motility while also having antiemetic effects. It can be helpful in treating nausea, particularly in cases where delayed gastric emptying is involved.

Each of these medications has specific indications and potential side effects, but they all share a common use in the management of nausea during pregnancy. Thus, they can be viewed collectively as options for treating this common issue in pregnant patients.